CBD, or cannabidiol, is one of several naturally occurring phytocannabinoids found in cannabis. Sourced primarily from the flowers and leaves of the plant, CBD is one of 80+ phyto- cannabinoids that is found in the Cannabis sativa species that includes both the hemp and marijuana plant. CBD is the most abundant cannabinoid found in hemp and the second-most abundant cannabinoid found in marijuana (after THC) and contains several therapeutic benefits. Unlike THC, however, CBD is non-psychoactive.
CBD works largely with the body’s own endocannabinoid system, which is responsible for the regulation of several physiological and psychological functions. One of the primary functions of the endocannabinoid system is to bring overall homeostasis (balance) to the body by modulating things such as sleep, pain, appetite, and mood. The endocannabinoid system has a complex action on the nervous and immune system and is found throughout the entire body, including the brain, connective tissues, organs, glands, immune cells, and skin.
Fatty-acid based particles anandamide (AEA) and 2-arachidonoylglycerol (2-AG) that bind with receptors in the endocannabinoid system. Endocannabinoids are cannabinoids naturally produced in the human body.
CB1 and CB2 receptors are found throughout the human body and are thought to be the most abundant type of receptor that exists. CB1 receptors are found in the brain, central and peripheral nervous systems, white blood cells, connective tissues, organs, and parts of the reproductive, gastrointestinal, and urinary tracts. CB2 receptors are primarily found in the immune system, spleen, tonsils, and the gastrointestinal system.
The enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGL) help break down excess endocannabinoids contained within the endocannabinoid system, particularly AEA.
CBD and other cannabinoids work in harmony with the cannabinoid receptors that are a primary element of the endocannabinoid system. This allows for the maintenance of balanced mental and physical well-being by supporting the body’s physiological processes. As we mentioned, CBD is non-psychoactive, which means it doesn’t get you “high” like THC. This is because THC is an agonist (activator) of the CB1 receptor, which is believed to be the key target in the brain that is responsible for generating intoxication. The reason CBD doesn’t make you feel high is that unlike THC, CBD does not activate the CB1 receptor. Instead, research indicates that it works as a CB1 antagonist, essentially inhibiting the activity of this receptor.
CBD affects each person differently. Everyone has different needs, and CBD works in harmony with your own endocannabinoid system to provide balance to whatever it is you need personally. That being said, everyone will have a different response when taking CBD. That being said, the effects of CBD will be personalized to meet your individual needs. Some might feel less anxious and more relaxed, while others feel a heightened sense of focus and concentration. How will CBD make you feel? It all depends on what your body needs.
Cannabidiol (CBD) and tetrahydrocannabinol (THC) are the two most common cannabinoids found in the Cannabis sativa plant family that includes hemp and marijuana. While the two popular cannabinoids are part of the same family and have the exact same chemical makeup, a slight difference in their molecular structure makes the two compounds react quite differently in the body. CBD and THC, naturally-occurring cannabinoids found in cannabis, interact with the bodys endocannabinoid system to help us maintain several vital functions throughout the body. Cannabinoid receptors in the endocannabinoid system are known as CB1 and CB2 receptors, and CBD, THC, and other cannabinoids interact with these receptors. This interaction is what allows for the myriad of health benefits both CBD and THC contain. Remember, CBD and THC have a slight difference in their molecular structure. Because of this slight difference, they dont interact with the CB1 and CB2 receptors in the same way. This is what makes the effect each cannabinoid has on the body so different. Let’s take a deeper look.
When purchasing CBD, you’ll come across options for both full spectrum CBD and CBD isolate. While both full spectrum CBD and CBD isolate do contain CBD, there are significant differences between the two. Let’s take a deeper look.
CBD oil that is referred to as “full spectrum” is that which contains all the various compounds found in cannabis. Full of Cannabinoids, terpenes, flavonoids, and more, full spectrum CBD provides the natural benefits of the plant. Many contend that full spectrum CBD is superior to CBD isolate, as the compounds full spectrum CBD contains work synergistically to create what is known as the entourage effect. Simply put, the entourage effect is when each compound in cannabis works together to strengthen its therapeutic effects.
CBD is actually one of several phytocannabinoids present in cannabis. In fact, there are over 100 cannabinoids that have been discovered in hemp. Some of the most common phytocannabinoids present in full spectrum CBD include:
Something else full spectrum contains is the terpenes that are naturally occurring in the cannabis plant. What exactly are terpenes? And why are they beneficial when it comes to CBD oil? Terpenes are part of a class of compounds called aromatic hydrocarbons and are an important component of cannabis (and other plant) resins. Terpenes are the aromatic compounds that are responsible for the smell of cannabis and other plants. They also contain therapeutic benefits of their own. Terpenes are known to work with various cannabinoids to create the entourage effect. Research has discovered that terpenes “could produce synergy with respect to treatment of pain, inflammation, depression, anxiety, addiction, fungal and bacterial infections.” A 2007 study, for example, found that terpenes have a broad range of biological properties that include:
Full spectrum CBD also contains trace amounts of THC (0.3% or less). While this isn’t enough to produce any psychoactive effects (the “high” associate with marijuana), there are individuals who would rather use CBD where all THC has been removed. These are the individuals who could benefit from using CBD isolate, a product where everything is stripped from the oil, except for the CBD. Our full spectrum CBD is a bit different, however. Using a proprietary extraction process, we’re able to provide a full spectrum CBD oil that contains zero THC, yet is still rich in other beneficial phytocannabinoids, terpenes, and other beneficial plant compounds. By removing any trace amounts of THC, we’re able to offer a full spectrum product that can confidently be used by anyone.
CBD isolate is pure CBD and nothing more. To isolate CBD from all the other compounds present in cannabis, a process known as chromatography is used. This strips away everything (including other cannabinoids, terpenes, and other plant compounds) except for CBD. The outcome is an odorless and tasteless white powder that contains 99% CBD. CBD isolate is considered to be the “purest” form of CBD you can find. It is typically less expensive than full spectrum CBD products, as it doesn’t contain any of the other naturally occurring plant compounds present in cannabis. There are individuals that prefer CBD isolate to full spectrum products as they contain zero trace amounts of THC, are odorless and tasteless, can be measured precisely for dosage control, and ultimately contain a lower cost per milligram. CBD isolate does not, however, contain any of the other therapeutic benefits and synergistic effects contained in full spectrum CBD products.
CBD (cannabidiol) is the most abundant cannabinoid found in hemp, and the second-most abundant cannabinoid found in marijuana. Of 80+ phytocannabinoids discovered in cannabis over the past 50 years, CBD is one of the most popular that exists. CBD has shown to contain several therapeutic benefits and is well-known for its anti-inflammatory, pain-relieving, anxiolytic, and neuroprotective properties.
There are several therapeutic benefits associated with CBD. Some of the most common reasons people use CBD are: reducing anxiety, increasing focus and concentration, pain relief, reducing inflammation, helping with neurological disorders such as overcoming addiction, treating various skin conditions, and more.
CBD holds possible benefit for just about everyone, which is why there are several different types of CBD products available. The most popular form of CBD, however, is likely CBD oil tincture that is taken sublingually (under the tongue). CBD oil can also be used in a vaporizer. Other kinds of CBD products include: capsules or supplements, syrups, edibles (gummies, chocolate, candy, etc.), beverages, topicals (creams, salves, lotions, balms, etc.), concentrates, suppositories, and crystals.
The short answer to this question is no. CBD is considered non-psychoactive, which means it will not get you high. That being said, CBD can have an effect on your mental state. Many people that use CBD have reported increased feelings of relaxation, focus, clarity, or alertness. But as far as getting you “high” like THC does, CBD simply doesn’t do it.
CBD products that contain zero THC (CBD isolate) will not show up on a drug tests that are designed to detect the psychoactive cannabinoid. There are many CBD products, however, that contain trace amounts of THC (0.3% or less).Unless full-spectrum CBD has gone through additional processing to remove all traces of THC (while leaving other cannabinoids intact), there is the possibility that it could show up on a drug test. Anyone concerned about minute amounts of THC showing up on a drug test after taking CBD should use products made with CBD isolate.
The legal status of CBD has been a grey area since the industry began. CBD containing less than 0.3% THC is legal in states that allow the use of hemp products. CBD that contains less than 0.3% THC is legal in states with medical and/or recreational marijuana laws. The passing of the 2018 Farm Bill federally legalized hemp and hemp-derived products, which should clear up any confusion on the legality of CBD.
There are a few different ways to take CBD. The main methods of CBD ingestion include: sublingual tinctures, capsules or supplements, vaporizing or smoking, edibles, and topical application.
Vaping, sublingual tinctures, concentrates, and topicals offer the most rapid results when taking CBD. Vaping and sublingual tinctures offer rapid relief because they bypass the digestive tract and liver altogether, reaching the bloodstream faster. Topicals work quickly to provide targeted relief as they work directly with the endocannabinoid system present in the skin. These methods can work in as few as 5-10 minutes, and the effects can last 1-3 hours.
Everyone has different needs when it comes to taking CBD. If you’re looking for a product that offers extended relief, edibles and capsules or supplements are the way to go. While these methods of delivery do take longer to kick in because they must first make their way through the digestive tract and liver before making their way into the bloodstream, the effects tend to last much longer (3-4 hours or longer).
CBD tincture is one of the most popular methods of ingestion and is taken by placing CBD oil under the tongue in the dropper provided with your bottle. CBD tincture should be held under the tongue for 60-90 seconds, so it may better absorb. This sublingual method of delivery allows for CBD to be absorbed my the mucous membranes where it is then directly absorbed into the bloodstream, bypassing the digestive tract completely and increasing its bioavailability.
Terpenes are a word that comes up a lot with CBD. Terpenes are the essential oils contained in plants. In the cannabis plant, there have been over 200 terpenes identified and are what’s responsible for giving cannabis its distinct aroma and flavor. Various terpenes have different therapeutic effects and have shown to work synergistically with CBD (and THC) in what is known as the “entourage effect.”
The endocannabinoid system is present in all vertebrae species. It is made up of endocannabinoids (naturally occurring cannabinoids found in the body), cannabinoid receptors, and enzymes that are help produce and breakdown cannabinoids. The most well-known endocannabinoids are anandamide and 2-AG, while the most well-known cannabinoid receptors are CB1 and CB2 receptors. CB1 receptors are found primarily in the brain and nervous system, while CB2 receptors are found primarily in the immune and gastrointestinal systems.